Kawasaki disease
Epidemiology
Etiology
Pathophysiology
Clinical features
- Fever ≥ 5 days; Usually > 39°C
(A) Bilateral, nonpurulent conjunctivitis
(B) Stomatitis with bright red lips
(C) Erythema and edema of the hands
(D) Erythema and edema of the feet
(E) Truncal rash
(F) Cervical lymphadenopathy
(G) Ultrasound of an enlarged cervical lymph node: increased perfusion
(H) Desquamation of fingertips
(I) Deep grooves in the nail (Beau lines)
Tip
Always consider Kawasaki disease in small children with a rash and high fever unresponsive to antibiotics.
Diagnostics
Treatment
Complications
- Coronary artery aneurysm
- The risk of developing coronary artery aneurysm in untreated patients is 15–25%
- Rupture or thrombosis of the aneurysm can be lethal.
- Myocardial infarction
- Myocarditis
- Ventricular dysfunction